Tuesday:

Hull City vs Newcastle United.

Newcastle United take on Premier League strugglers Hull City at the KCOM stadium on Tuesday. The Championship leaders, whose 11-game unbeaten run was ended by Blackburn Rovers at the weekend, will be hoping to progress to their first domestic cup semi-final since 2005 when they lost to Manchester United in the FA Cup at the Millenium stadium. Hull, who find themselves in the Premier League relegation zone will be hoping to continue their good form in the competition which has seen them win three away games so far.

Liverpool vs Leeds United

Eight-times winners Liverpool are up against promotion-chasing Leeds United. The Merseyside club, who lost last season's final on penalties against Manchester City will be without star player Phillip Coutinho. The Brazilian forward was stretchered off during their 2-0 win over Sunderland on Saturday and could be facing a lengthy period on the sidelines. Leeds, who last won the competition in 1968 will be hoping to continue their impressive form that has seen them rise to fifth in the Championship. The West Yorkshire club has so far won two penalty shootouts on their way to the Quarter Finals.

Wednesday:

Arsenal vs Southampton.

Arsene Wenger is chasing the one domestic title that he has so far failed to win in his time at Arsenal.

The Gunners haven't won the League Cup since 1993 and lost their last final in 2011 to Birmingham City, who later that season were relegated from the top flight. Southampton, who will be looking to improve on last season's result at this stage, when they were soundly beaten at home 6-1 by finalists Liverpool, come into the game off the back of an impressive performance and 1-0 victory over Everton on Sunday.

The South Coast club will be hoping to avenge the corresponding fixture from earlier in the season when they lost to a 94th-minute penalty from Santi Cazorla that gave Arsenal the three points.

Manchester United vs West Ham United.

For the second time in four days, these two clubs meet at Old Trafford. Manchester United will be without the suspended Paul Pogba, whose yellow card on Sunday resulted in Jose Mourinho being sent from the dugout for the second time this month.

Both sides progressed to the Quarter Finals after home victories over local rivals. United beat Manchester City 1-0 after a Juan Mata goal, and West Ham beat Chelsea at the London Stadium 2-1 in a game that was marred by crowd trouble towards the end of the fixture. West Ham, who have twice been losing finalists in the League Cup will be aiming to record their first win at Old Trafford since 2007 when a Carlos Tevez goal secured their safety in the Premier League.